TBPL1 抗体
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- 抗原 See all TBPL1 抗体
- TBPL1 (TBP-Like 1 (TBPL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TBPL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Protein G Chromatography
- 免疫原
- Full length recombinant TRF2 protein was used as the immunogen for this antibody.
- 克隆位点
- ABM10H3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TBPL1 Primary Antibody
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anti-TBP-Like 1 (TBPL1) antibody
TBPL1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (AA 1-186) antibodyTBPL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (AA 88-137) antibodyTBPL1 适用: 人, 小鼠, 大鼠, 猴, 犬, Cow, 马, 兔, 豚鼠, Bat, Pig, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (AA 1-186) antibodyTBPL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) antibodyTBPL1 适用: 人 WB, ELISA, IHC, IP, FACS, ChIP, FM 宿主: 小鼠 Monoclonal 4A794-15 unconjugated
anti-TBP-Like 1 (TBPL1) (AA 301-400) antibodyTBPL1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (AA 1-185) antibodyTBPL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) antibodyTBPL1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (C-Term) antibodyVerified TBPL1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TBP-Like 1 (TBPL1) (Middle Region) antibodyTBPL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- TBPL1 (TBP-Like 1 (TBPL1))
- 别名
- TRF2 (TBPL1 产品)
- 别名
- MGC:8389 antibody, MGC:9620 antibody, STUD antibody, TLF antibody, TLP antibody, TRF2 antibody, tlf antibody, 4732475G08 antibody, AW011832 antibody, AW491032 antibody, D18347 antibody, STD antibody, TRP antibody, Tlp antibody, tlp antibody, trf antibody, trf2 antibody, trp antibody, zgc:92340 antibody, TATA binding protein 1 antibody, TFIID-1 antibody, TRANSCRIPTION FACTOR IID-1 antibody, TATA-box binding protein like 1 antibody, TATA-binding protein 1 antibody, TATA-box binding protein like 1 L homeolog antibody, TATA box binding protein-like 1 antibody, TBP-like 1 antibody, TATA binding protein 1 antibody, TBPL1 antibody, tbp1 antibody, tbpl1.L antibody, tbpl1 antibody, Tbpl1 antibody, TBP1 antibody
- 背景
- TRF2 (Telomere Repeat Binding Factor 2), a subunit of the shelterin complex, binds to duplex telomeric DNA and plays a crucial role in telomere protection. TRF2 contains an N-terminal basic domain rich in glycines and arginines (the GAR domain), a central TRFH dimerization domain, a flexible linker region and a C-terminal Myb-like DNA binding domain. TRF2 undergoes extensive post-translational modification, which in turn regulates its stability, DNA binding and cellular localization. Ubiquitylation of TRF2 by Siah1, an E3 ligase, promotes TRF2 degradation and replicative senescence of human primary fibroblasts. TRF2 is phosphorylated in response to DNA damage and this phosphorylation has been implicated in DNA double strand break repair.
- 分子量
- 50 kDa
- 基因ID
- 7014
- UniProt
- Q15554
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