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SPIB 抗体

SPIB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027786
发货至: 中国
  • 抗原 See all SPIB 抗体
    SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
    适用
    • 24
    • 22
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    宿主
    • 36
    • 1
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    This SPIB antibody is un-conjugated
    应用范围
    • 37
    • 18
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    Full length recombinant SpiB protein was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product SPIB Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
    别名
    SpiB (SPIB 产品)
    别名
    spi-b antibody, spib antibody, spiba antibody, SPI-B antibody, B42b-like antibody, Spi-B antibody, Spi-B transcription factor L homeolog antibody, Spi-B transcription factor antibody, Spi-B transcription factor (Spi-1/PU.1 related) antibody, spib.L antibody, SPIB antibody, Spib antibody
    背景
    Spi-B belongs to the ETS family transcription factor containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) and is localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N-terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.
    分子量
    28 kDa
    基因ID
    6689
    UniProt
    Q01892
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