MERS-Coronavirus Spike 抗体
MERS-CoV S
适用: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
WB
宿主: 小鼠
Monoclonal
ABM4A80
unconjugated
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- 抗原 See all MERS-Coronavirus Spike (MERS-CoV S) products
- MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))
- 适用
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MERS-Coronavirus Spike antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A recombinant protein fragment of MERS-CoV Spike (S) protein was used as the immunogen for this antibody.
- 克隆位点
- ABM4A80
- 亚型
- IgG2b kappa
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anti-MERS-Coronavirus Spike Protein (MERS-CoV S) (AA 381-505) antibody
MERS-CoV S 适用: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) WB 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- WB: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))
- 别名
- MERS-CoV Spike (S) protein (MERS-CoV S 产品)
- 物质类
- Viral Protein
- 背景
- The MERS-CoV spike (S) protein is a type I transmembrane glycoprotein which contains 1353 amino acids and can be cleaved into two subunit S1 and S2. It forms large protruding spikes on the surface of the virus. The S1 subunit which contains RBD is responsible for binding to Dipeptidyl peptidase 4, which serves as the host cell receptor of MERS-CoV and S2 mediates the membrane fusion. In this process, heptad repeats 1 and 2 (HR1 and HR2) of the S protein assemble into a complex called six-helix bundle (6-HB) fusion core structure, which represents a key membrane fusion architecture. Importantly, the S protein is considered a key component of vaccines against coronavirus infection, including severe acute respiratory syndrome (SARS).
- 分子量
- 28 kDa
- UniProt
- W5ZZU6
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