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RUNX2 抗体 (AA 161-482)

The 兔 多克隆 anti-RUNX2 antibody is suitable to detect RUNX2 in samples from 人. It has been validated for WB.
产品编号 ABIN5027509
发货至: 中国
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Quick Overview for RUNX2 抗体 (AA 161-482) (ABIN5027509)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 161-482

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant RUNX2 protein (amino acids 161-482) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 1-3 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Runt-related transcription factor 2 (Runx2) is also known as core-binding factor subunit alpha-1 (CBF-alpha-1). RunX2 is one of the three mammalian transcription factors sharing the highly conserved DNA-binding Runt domain that represents a key class of lineage-specific gene regulators and is associated with different micro-environments during the cell cycle. RUNX2 has a primary role in the differentiation of osteoblasts and hypertrophy of cartilage at the growth plate, cell migration and vascular invasion of bone and is also expressed in vascular endothelial cells and breast cancer cells. It is a heterodimer of an alpha and a beta subunit. RUNX2 plays a role in the disease metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly, and cleidocranial dysplasia. By alternative splicing, several isoforms exist.

    分子量

    50 kDa

    基因ID

    860

    UniProt

    Q13950
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