VTCN1 抗体 (AA 23-220)
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- 抗原 See all VTCN1 抗体
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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抗原表位
- AA 23-220
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This VTCN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A partial length recombinant protein (a.a 23-220) of B7-H4 was used as the immunogen for this antibody.
- 克隆位点
- ABM53A6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product VTCN1 Primary Antibody
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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 50-100) antibody
VTCN1 适用: 人 ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 WB, ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal B7H4-1788 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 153-241) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 ELISA, IHC, FACS, IF, Coat, StM 宿主: 兔 Monoclonal B7H4-2652R unconjugated Recombinant Antibody
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Internal Region) antibodyVerified VTCN1 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) antibodyVTCN1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3A9C12 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- FACS: 0.5-1 μg/10^6 cells, IHC: 5 μg/mL, WB: 2-4 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
- 别名
- B7H4 (VTCN1 产品)
- 别名
- B7h4 antibody, B7s1 antibody, B7x antibody, BC032925 antibody, B7-H4 antibody, B7H4 antibody, B7S1 antibody, B7X antibody, B7h.5 antibody, PRO1291 antibody, VCTN1 antibody, RGD1311204 antibody, V set domain containing T cell activation inhibitor 1 L homeolog antibody, V-set domain containing T cell activation inhibitor 1 antibody, V-set domain containing T-cell activation inhibitor 1 antibody, V set domain containing T cell activation inhibitor 1 antibody, vtcn1.L antibody, VTCN1 antibody, vtcn1 antibody, Vtcn1 antibody
- 背景
- B7-H4, a member of B7 family, is a transmembrane protein that has been shown to inhibit T cell responses and neutrophil expansion during bacterial infections. B7-H4 mRNA is widely distributed in mouse and human peripheral tissues and can be induced in monocytes, macrophages, and dendritic cells upon IL-6 and IL-10 stimulation. However, in a variety of tumor cells, B7-H4 is predominantly present in intracellular compartments with unknown mechanism and functions. Cell surface expression of B7-H4 protein is limited and shows an inducible pattern on hematopoietic cells. The overexpression of B7-H4 has been found in various types of human tumors, such as breast cancer, renal cell carcinoma (RCC), ovarian cancer, esophageal squamous cell carcinoma, gastric cancer, pancreatic cancer and melanoma etc, where its expression level is positively correlated with disease progression. By arresting cell cycle, B7-H4 ligation of T cells has a profound inhibitory effect on the growth, cytokine secretion, and development of cytotoxicity.
- 分子量
- 75 kDa
- 基因ID
- 79679
- UniProt
- Q7Z7D3
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