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Napsin (AA 150-350) 抗体

适用: 人 IHC, WB 宿主: 小鼠 Monoclonal ABM4H60 unconjugated
产品编号 ABIN5027389
发货至: 中国
  • 抗原
    Napsin
    抗原表位
    AA 150-350
    适用
    宿主
    • 1
    小鼠
    克隆类型
    • 1
    单克隆
    标记
    • 1
    非结合性
    应用范围
    Immunohistochemistry (IHC), Western Blotting (WB)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant Napsin protein (amino acids 150-350) was used as the immunogen for this antibody
    克隆位点
    ABM4H60
    亚型
    IgG1 kappa
  • 应用备注
    WB: 0.5-1 μg/mL, IHC: 5-10 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    Napsin
    背景
    Napsin A, a human aspartic proteinase is found primarily in type II pneumocytes and alveolar macrophages and predominantly expressed in lung and kidney. It is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). It is also useful in evaluating SH (Sclerosing hemangiomas) (23194051). Napsin A acts as an anti-apoptotic protein that promotes resistance to cisplatin by degradation of the tumor suppressor p53, which is regulator of the cell cycle and co-works with cyclin kinase inhibitors as p21 and p27.
    分子量
    44 kDa
    基因ID
    9476
    UniProt
    O96009
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