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GBL 抗体 (AA 100-320)
GBL
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
GBL抗体详情
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抗原
See all GBL 抗体
GBL
(G protein beta subunit-like (GBL))
抗原表位
All epitopes for GBL 抗体
AA 100-320
适用
All reactivities for GBL 抗体
人
宿主
All hosts for GBL 抗体
兔
克隆类型
All clonalities for GBL 抗体
多克隆
标记
All conjugates for GBL 抗体
This GBL antibody is un-conjugated
应用范围
All applications for GBL 抗体
Western Blotting (WB)
纯化方法
Protein A Chromatography
免疫原
A partial length recombinant LST8/GBL protein (amino acids 100-320) was used as the immunogen for this antibody.
亚型
IgG
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Alternatives
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anti-G protein beta subunit-like (GBL) (C-Term) antibody
GBL
适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1-3 μg/mL.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
PBS containing 0.05 % BSA, PH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
GBL目标详情
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抗原
GBL
(G protein beta subunit-like (GBL))
别名
LST8/GBL (GBL 产品 )
别名
gbl antibody, lts8 antibody, GBL antibody, GbetaL antibody, LST8 antibody, POP3 antibody, WAT1 antibody, 0610033N12Rik antibody, AA409454 antibody, AI505104 antibody, AI851821 antibody, Gbl antibody, fi37e04 antibody, wu:fi37e04 antibody, zgc:55455 antibody, zgc:85668 antibody, MTOR associated protein, LST8 homolog L homeolog antibody, MTOR associated protein, LST8 homolog antibody, MTOR associated protein, LST8 homolog (S. cerevisiae) antibody, mlst8.L antibody, MLST8 antibody, Mlst8 antibody, mlst8 antibody
背景
MLST8 or GbL (G protein beta protein subunit-like) is a subunit of mTORC1 and mTORC2 which regulates cell growth and survival. Both mTORC1 and 2 are activated in response to growth factors or amino acids but mTORC2 is most likely insensitive towards nutrients. Within mTORC1, LST8 interacts directly with mTOR and helps to enhance its kinase activity. mTORC1 phosphorylates EIF4EBP1 and thereby releasing it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. LST8/GBL more or less ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
分子量
38 kDa
基因ID
64223
UniProt
Q9BVC4
途径
PI3K-Akt Signaling , RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , Autophagy , CXCR4-mediated Signaling Events , BCR Signaling , Warburg Effect
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