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GBL 抗体 (AA 100-320)

GBL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027338
发货至: 中国
  • 抗原 See all GBL 抗体
    GBL (G protein beta subunit-like (GBL))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 100-320
    适用
    • 51
    • 33
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 62
    • 3
    • 2
    克隆类型
    • 66
    • 1
    多克隆
    标记
    • 28
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GBL antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 13
    • 13
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant LST8/GBL protein (amino acids 100-320) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product GBL Primary Antibody
  • 应用备注
    WB: 1-3 μg/mL.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    GBL (G protein beta subunit-like (GBL))
    别名
    LST8/GBL (GBL 产品)
    别名
    gbl antibody, lts8 antibody, GBL antibody, GbetaL antibody, LST8 antibody, POP3 antibody, WAT1 antibody, 0610033N12Rik antibody, AA409454 antibody, AI505104 antibody, AI851821 antibody, Gbl antibody, fi37e04 antibody, wu:fi37e04 antibody, zgc:55455 antibody, zgc:85668 antibody, MTOR associated protein, LST8 homolog L homeolog antibody, MTOR associated protein, LST8 homolog antibody, MTOR associated protein, LST8 homolog (S. cerevisiae) antibody, mlst8.L antibody, MLST8 antibody, Mlst8 antibody, mlst8 antibody
    背景
    MLST8 or GbL (G protein beta protein subunit-like) is a subunit of mTORC1 and mTORC2 which regulates cell growth and survival. Both mTORC1 and 2 are activated in response to growth factors or amino acids but mTORC2 is most likely insensitive towards nutrients. Within mTORC1, LST8 interacts directly with mTOR and helps to enhance its kinase activity. mTORC1 phosphorylates EIF4EBP1 and thereby releasing it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. LST8/GBL more or less ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
    分子量
    38 kDa
    基因ID
    64223
    UniProt
    Q9BVC4
    途径
    PI3K-Akt Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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