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FOXO1 抗体

FOXO1 适用: 人 WB 宿主: 小鼠 Monoclonal ABM4E66 unconjugated
产品编号 ABIN5026986
发货至: 中国
  • 抗原 See all FOXO1 抗体
    FOXO1 (Forkhead Box O1 (FOXO1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FOXO1 antibody is un-conjugated
    应用范围
    • 190
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    Western Blotting (WB)
    纯化方法
    Protein G Chromatography
    免疫原
    A full length recombinant FOXO1 protein was used as the immunogen for this antibody.
    克隆位点
    ABM4E66
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FOXO1 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    FOXO1 (Forkhead Box O1 (FOXO1))
    别名
    FOXO1 (FOXO1 产品)
    别名
    FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody
    背景
    FOXO1 is one of the fox proteins playing pivotal roles in several human intracellular pathways. These proteins are transcription factors acting as nuclear regulator of transcriptional activity of a number of metabolic processes such as the cellular response to oxidative stress. FOXO1 protein response to oxidative stress may be linked to Alzheimer's disease (AD) by means of insulin brain resistance. FOXO1 plays a critical role in establishing and maintaining the B cell specific differentiation program, but it is also responsible for cell death due to an inappropriate BCR signaling. This protein is highly expressed in B cells, is downregulated in Hodgkin and Reed-Sternberg (HRS) cells of cHL (Classical Hodgkin Lymphoma).
    分子量
    70 kDa
    基因ID
    2308
    UniProt
    Q12778
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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