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ZC3H12A 抗体 (Center)

ZC3H12A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501151
发货至: 中国
  • 抗原 See all ZC3H12A 抗体
    ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
    抗原表位
    • 16
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 40
    • 18
    • 2
    • 1
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    • 1
    宿主
    • 39
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 16
    • 4
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ZC3H12A antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 17
    • 13
    • 13
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects human ZC3H12A.
    纯化方法
    Affinity chromatography
    免疫原
    ZC3H12A antibody was raised against a 17 amino acid peptide near the center of human ZC3H12A.
    亚型
    IgG
    Top Product
    Discover our top product ZC3H12A Primary Antibody
  • 应用备注
    ELISA. Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
    别名
    ZC3H12A (ZC3H12A 产品)
    别名
    CGA antibody, MCPIP antibody, MCPIP1 antibody, RP3-423B22.1 antibody, dJ423B22.1 antibody, BC036563 antibody, Mcpip1 antibody, RGD1306776 antibody, chromogranin A antibody, zinc finger CCCH-type containing 12A antibody, zinc finger CCCH type containing 12A antibody, CHGA antibody, ZC3H12A antibody, Zc3h12a antibody
    背景
    ZC3H12A, also known as MCPIP, is an essential member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. ZC3H12A has RNase activity that prevents some immune disorders by directly affecting the mRNA stability of interleukins such as IL-6 and IL12p40. Mice lacking the ZC3H12A gene suffered from severe anemia, and most dies within 12 weeks. Overexpression of ZC3H12A causes ER stress and induces a number of genes involved in apoptosis and autophagy, including JNK, PUMA, and beclin-1 in cardiac myoblasts, leading to cell death. ZC3H12A can also induce adipogenesis in 3T3-L1 pre-adipocytes in the absence of PPAPg, demonstrating the complex roles ZC3H12A plays.Synonyms: MCP-induced protein 1, MCPIP, MCPIP1, Ribonuclease ZC3H12A, Zinc finger CCCH domain-containing protein 12A
    基因ID
    80149
    NCBI登录号
    NP_079355
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of fat Cell Differentiation
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