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TRAF6 抗体 (C-Term)

TRAF6 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501028
发货至: 中国
  • 抗原 See all TRAF6 抗体
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    抗原表位
    • 15
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 57
    • 30
    • 25
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 56
    • 4
    • 2
    克隆类型
    • 54
    • 8
    多克隆
    标记
    • 39
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAF6 antibody is un-conjugated
    应用范围
    • 58
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TRAF6 / RNF85 at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Ion exchange chromatography
    免疫原
    TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
    亚型
    IgG
    Top Product
    Discover our top product TRAF6 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    别名
    TRAF6 / RNF85 (TRAF6 产品)
    背景
    Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
    基因ID
    7189
    NCBI登录号
    NP_004611
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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