TRAF6 抗体 (C-Term)
Quick Overview for TRAF6 抗体 (C-Term) (ABIN501028)
抗原
See all TRAF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TRAF6 / RNF85 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Ion exchange chromatography
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免疫原
- TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
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亚型
- IgG
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anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 153-423) antibody
TRAF6 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 413-522) antibodyTRAF6 适用: 人 WB, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 263-522) antibodyTRAF6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (Middle Region) antibodyTRAF6 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 441-530) antibodyTRAF6 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 314-343) antibodyTRAF6 适用: 人 WB 宿主: 兔 Polyclonal RB40708 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (C-Term) antibodyTRAF6 适用: 人, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
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别名
- TRAF6 / RNF85
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背景
- Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
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基因ID
- 7189
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NCBI登录号
- NP_004611
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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