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TLR8 抗体 (Middle Region)

This anti-TLR8 antibody is a 兔 多克隆 antibody detecting TLR8 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500964
发货至: 中国

Quick Overview for TLR8 抗体 (Middle Region) (ABIN500964)

抗原

See all TLR8 抗体
TLR8 (Toll-Like Receptor 8 (TLR8))

适用

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人, 小鼠

宿主

  • 81
  • 14
  • 2
  • 1

克隆类型

  • 83
  • 15
多克隆

标记

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This TLR8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 20
    • 15
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    • 8
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    Middle Region

    特异性

    This antibody detects CD288 / TLR8 at center.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Peptide affinity chromatography

    免疫原

    TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TLR8 (Toll-Like Receptor 8 (TLR8))

    别名

    CD288 / TLR8

    背景

    Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).Synonyms: Toll-like receptor 8, UNQ249/PRO286

    基因ID

    51311

    NCBI登录号

    NP_619542

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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