RAB5 抗体 (AA 8-100) (Alexa Fluor 750)
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- 抗原 See all RAB5 (RAB5A) 抗体
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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抗原表位
- AA 8-100
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB5 antibody is conjugated to Alexa Fluor 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RAB5.
- 亚型
- IgG
- Top Product
- Discover our top product RAB5A Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
- 别名
- RAB5 (RAB5A 产品)
- 别名
- RAB5 antibody, 2410015H04Rik antibody, AI663973 antibody, AU021172 antibody, nnyRab5a antibody, DDBDRAFT_0168594 antibody, DDBDRAFT_0229401 antibody, DDB_0168594 antibody, DDB_0229401 antibody, rab5 antibody, RAB5A antibody, Rab5a antibody, rab5al antibody, zgc:56644 antibody, fj38g08 antibody, hm:zehn1144 antibody, rab5a antibody, wu:fj38g08 antibody, RAB5A, member RAS oncogene family antibody, rab5A protein antibody, Rab5a, GTPase antibody, predicted protein antibody, Rab GTPase antibody, RAB5A, member RAS oncogene family L homeolog antibody, RAB5A, member RAS oncogene family, b antibody, RAB5A, member RAS oncogene family, a antibody, RAB5A antibody, Rab5a antibody, rab5A antibody, rab5a antibody, rab5a.L antibody, rab5ab antibody, rab5aa antibody
- 背景
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Synonyms: RAB 5, RAB 5A, RAB5A, RAB5A member RAS oncogene family, RAB5A_HUMAN, RAS associated protein RAB5A, Ras related protein Rab 5A, Ras-related protein Rab-5A.
Background: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
- 基因ID
- 5868
- 途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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