PLC gamma 1Tyr775 (pTyr775) 抗体 (Alexa Fluor 680)
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- 抗原
- PLC gamma 1Tyr775
- 抗原表位
- pTyr775
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 680
- 应用范围
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr775
- 亚型
- IgG
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-
- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PLC gamma 1Tyr775
- 背景
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Synonyms: PLCG1phospho Y775, PLC 1, PLC 148, PLC gamma 1, PLC II, PLC1, PLC148, PLCG 1, PLCG1, PLCgamma1, PLCII, triphosphoinositide phosphodiesterase, 1 phosphatidyl D myo inositol 4 5 bisphosphate, 1 phosphatidylinositol 4 5 bisphosphate, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, phosphodiesterase gamma 1, phosphoinositidase C, phosphoinositide phospholipase C, Phospholipase C 148, phospholipase C gamma 1 formerly subtype 148, Phospholipase C gamma 1, phospholipase C-148, PLCG1_HUMAN.
Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- 基因ID
- 5335
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