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PPAPDC1B 抗体 (N-Term)

PPAPDC1B 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500529
发货至: 中国
  • 抗原 See all PPAPDC1B 抗体
    PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPAPDC1B antibody is un-conjugated
    应用范围
    • 21
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PPAPDC1B.
    纯化方法
    Peptide affinity chromatography
    免疫原
    PPAPDC1B antibody was raised against a 14 amino acid peptide near the amino terminus of human PPAPDC1B.
    亚型
    IgG
    Top Product
    Discover our top product PPAPDC1B Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))
    别名
    PPAPDC1B (PPAPDC1B 产品)
    别名
    PPAPDC1B antibody, DPPL1 antibody, HTPAP antibody, 1810019D05Rik antibody, 2310022A04Rik antibody, AW045471 antibody, Ppapdc1 antibody, phospholipid phosphatase 5 antibody, PLPP5 antibody, plpp5 antibody, Plpp5 antibody
    背景
    Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.Synonyms: DPPL1, HTPAP, Phosphatidate phosphatase PPAPDC1B, Phosphatidic acid phosphatase type 2 domain-containing protein 1B
    基因ID
    84513
    NCBI登录号
    NP_001096029
    UniProt
    Q8NEB5
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