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- 抗原 See all MYBPC2 抗体
- MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYBPC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2.
- 亚型
- IgG
- Top Product
- Discover our top product MYBPC2 Primary Antibody
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).
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Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).
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- 抗原
- MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))
- 别名
- MYBPC2 (MYBPC2 产品)
- 别名
- MYBPC antibody, MYBPCF antibody, im:7137115 antibody, im:7150089 antibody, zgc:110761 antibody, myosin binding protein C, fast-type antibody, myosin binding protein C, fast type antibody, myosin-binding protein C, fast-type antibody, myosin binding protein C, fast type b antibody, Mybpc2 antibody, MYBPC2 antibody, LOC520988 antibody, mybpc2b antibody
- 背景
- Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.Synonyms: C-protein, Fast MyBP-C, MYBPCF, Myosin-binding protein C, skeletal muscle fast isoform
- 基因ID
- 4606
- NCBI登录号
- NP_004524
- UniProt
- Q14324
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