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Survivin 抗体 (C-Term)

This anti-Survivin antibody is a 兔 多克隆 antibody detecting Survivin in WB, IHC (p) 和 EIA. Suitable for 小鼠.
产品编号 ABIN500292
发货至: 中国

Quick Overview for Survivin 抗体 (C-Term) (ABIN500292)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Survivin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects IAP4 / BIRC5 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    Survivin antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of mouse Survivin.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 to 2 μg/mL, an approximate 17 kDa band can be detected. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    IAP4 / BIRC5

    背景

    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1,3).Synonyms: API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, Survivin

    基因ID

    11799

    UniProt

    O70201

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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