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Ephrin A1 抗体 (AA 101-205) (AbBy Fluor® 680)

Name: Ephrin A1 抗体 (AA 101-205) (AbBy Fluor® 680)
SKU: ABIN5002036
Availability: OutOfStock

This anti-Ephrin A1 antibody is a 兔多克隆 antibody detecting Ephrin A1 in IF (cc) 和 IF (p). Suitable for 人.

产品编号 ABIN5002036

发货至: 中国

Datasheet as PDF

Quick Overview for Ephrin A1 抗体 (AA 101-205) (AbBy Fluor® 680) (ABIN5002036)

抗原

See all Ephrin A1 (EFNA1) 抗体

Ephrin A1 (EFNA1)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Ephrin A1 antibody is conjugated to AbBy Fluor® 680

应用范围

Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product EFNA1 Primary Antibody

抗原表位
14

6

6

4

2

1

1

1

1

1

1

1

1

1
AA 101-205

交叉反应

人

预测反应

Mouse,Rat

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Ephrin A1

亚型

IgG
anti-Ephrin A1 (EFNA1) antibody
EFNA1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (Internal Region) antibody
EFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (AA 19-182) antibody
EFNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) antibody
EFNA1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Ephrin A1 (EFNA1) (AA 150-164), (Extracellular) antibody
EFNA1 适用: 人 WB, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (AA 19-182) antibody
EFNA1 适用: 人 ELISA, WB, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (AA 19-182) antibody
EFNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) antibody
EFNA1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (Internal Region) antibody
EFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Ephrin A1 (EFNA1) (AA 101-205) antibody
EFNA1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

Ephrin A1 (EFNA1)

别名

Ephrin A1

背景

Synonyms: Ephrin-A1, EFNA1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, EPLG1, LERK1, TNFAIP4
Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

基因ID

1942

UniProt

P20827

途径

RTK signaling