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Girdin 抗体 (C-Term)

This anti-Girdin antibody is a 兔 多克隆 antibody detecting Girdin in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499889
发货至: 中国

Quick Overview for Girdin 抗体 (C-Term) (ABIN499889)

抗原

See all Girdin (CCDC88A) 抗体
Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

适用

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人, 小鼠, 大鼠

宿主

  • 57

克隆类型

  • 56
  • 1
多克隆

标记

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  • 1
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This Girdin antibody is un-conjugated

应用范围

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  • 4
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 27
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    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Girdin antibody was raised against a 16 amino acid peptide from near the carboxy terminus human Girdin.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

    别名

    Girdin

    背景

    Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development, depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.Synonyms: APE, Akt phosphorylation enhancer, CCDC88A, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIV, GRDN, Girders of actin filament, HkRP1, Hook-related protein 1, KIAA1212

    基因ID

    55704

    NCBI登录号

    NP_060554

    UniProt

    Q3V6T2
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