ELISA. Western Blot: CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 -2 μg/mL. Mouse heart cell lysate can be used as positive control. These proteins are oftenhighly modified post-translationally and migrate in SDS-PAGE at positions other than theirpredicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
抗原
C1QTNF3
(C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))
Amacr antibody, zgc:110704 antibody, C1ATNF3 antibody, CORCS antibody, CORS antibody, CORS-26 antibody, CORS26 antibody, CTRP3 antibody, 2310005P21Rik antibody, Corcs antibody, Cors antibody, C1q and tumor necrosis factor related protein 3 antibody, alpha-methylacyl-CoA racemase antibody, C1q and TNF related 3 antibody, C1QTNF3 antibody, amacr antibody, C1qtnf3 antibody
背景
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).Synonyms: C1ATNF3, CORS26, CTRP3, Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26