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AGXT2L2 抗体 (Alexa Fluor 680)

AGXT2L2 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Alexa Fluor 680
产品编号 ABIN4996230
发货至: 中国
  • 抗原 See all AGXT2L2 抗体
    AGXT2L2 (Alanine-Glyoxylate Aminotransferase 2-Like 2 (AGXT2L2))
    适用
    • 27
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    人, 小鼠, 大鼠
    宿主
    • 25
    • 2
    克隆类型
    • 27
    多克隆
    标记
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    This AGXT2L2 antibody is conjugated to Alexa Fluor 680
    应用范围
    • 27
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AGXT2L2
    亚型
    IgG
    Top Product
    Discover our top product AGXT2L2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    AGXT2L2 (Alanine-Glyoxylate Aminotransferase 2-Like 2 (AGXT2L2))
    别名
    AGXT2L2 (AGXT2L2 产品)
    别名
    AGXT2L2 antibody, PHLU antibody, Agxt2l2 antibody, 2900006B13Rik antibody, 5-phosphohydroxy-L-lysine phospho-lyase antibody, 5-phosphohydroxy-L-lysine phospholyase antibody, PHYKPL antibody, phykpl antibody, Phykpl antibody
    背景

    Synonyms: Alanine glyoxylate aminotransferase 2 like 2, MGC117348, AT2L2_HUMAN.

    Background: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.

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