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BCL2L1 抗体

This anti-BCL2L1 antibody is a 兔 多克隆 antibody detecting BCL2L1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN499435
发货至: 中国

Quick Overview for BCL2L1 抗体 (ABIN499435)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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克隆类型

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多克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    Bcl-xL antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human Bcl-xL.

    纯化方法

    Ion exchange chromatography

    免疫原

    Murine Bcl-xL Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    Bcl-2-Like 1

    背景

    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis (reviewed in 2 and 3). These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene (4). Its high expression in tumors is correlated with advanced disease and poor prognosis (5). Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents (6,7).Synonyms: BCL2L, BCL2L1, BCLX, Bcl-2-like protein 1, Bcl-x, Bcl2-L-1, bcl-xL, bcl-xS

    基因ID

    598

    UniProt

    Q07817

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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