电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

BAK1 抗体 (N-Term)

BAK1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499405
发货至: 中国
  • 抗原 See all BAK1 抗体
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    抗原表位
    • 18
    • 16
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 77
    • 31
    • 23
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 71
    • 4
    • 2
    • 1
    克隆类型
    • 63
    • 15
    多克隆
    标记
    • 44
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAK1 antibody is un-conjugated
    应用范围
    • 67
    • 27
    • 27
    • 19
    • 14
    • 14
    • 13
    • 12
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Bak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
    纯化方法
    Ion exchange chromatography
    免疫原
    Human Bak (N-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product BAK1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Bak antibody can be used for detection of Bak at 1 to 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    别名
    Bcl-2-Like 7 (BAK1 产品)
    别名
    BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
    背景
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria (4,5). It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability (6,7).Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1
    基因ID
    578
    UniProt
    Q16611
    途径
    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
You are here:
客服