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DRAK2 抗体 (Internal Region)

STK17B 适用: 人, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN499168
发货至: 中国
  • 抗原 See all DRAK2 (STK17B) 抗体
    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))
    抗原表位
    • 11
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 42
    • 16
    • 8
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 39
    • 2
    • 1
    山羊
    克隆类型
    • 41
    • 1
    多克隆
    标记
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DRAK2 antibody is un-conjugated
    应用范围
    • 30
    • 25
    • 8
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    序列
    C-HSVRSSEDKT SK
    特异性
    This antibody detects STK17B / DRAK2 (Internal).
    交叉反应 (详细)
    Species reactivity (expected):DogSpecies reactivity (tested):Human
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from the internal region of the protein sequence according to NP_004217.1
    Top Product
    Discover our top product STK17B Primary Antibody
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line MOLT4(calculated MW of 42.5 kDa according to NP_004217.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
  • 抗原
    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))
    别名
    STK17B / DRAK2 (STK17B 产品)
    别名
    zgc:65989 antibody, STK17B antibody, DRAK2 antibody, Drak2 antibody, 3110009A03Rik antibody, AI120141 antibody, serine/threonine kinase 17b (apoptosis-inducing) antibody, serine/threonine kinase 17b antibody, stk17b antibody, STK17B antibody, Stk17b antibody
    背景
    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP,are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain anN-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2, Serine/threonine-protein kinase 17B
    基因ID
    9262
    NCBI登录号
    NP_004217
    UniProt
    O94768
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