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NDUFS8 抗体 (Internal Region)

NDUFS8 适用: 人, 小鼠, 大鼠, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN499135
发货至: 中国
  • 抗原 See all NDUFS8 抗体
    NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))
    抗原表位
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 39
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 35
    • 3
    • 2
    山羊
    克隆类型
    • 40
    多克隆
    标记
    • 24
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDUFS8 antibody is un-conjugated
    应用范围
    • 29
    • 16
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-EAEIAANIQA D
    特异性
    Recognizes NDUFS8.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Canine.
    Species reactivity (tested):Human, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_002487.1. Genename: NDUFS8
    Top Product
    Discover our top product NDUFS8 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/4000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 25 kDa in Mouse and RatHeart lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))
    别名
    NDUFS8 (NDUFS8 产品)
    别名
    CI-23k antibody, CI23KD antibody, TYKY antibody, BC021616 antibody, CI-23kD antibody, ndufs8 antibody, wu:fb30b07 antibody, zgc:65835 antibody, zgc:77840 antibody, MGC85457 antibody, ND23 antibody, GB17476 antibody, DDBDRAFT_0169117 antibody, DDBDRAFT_0233205 antibody, DDB_0169117 antibody, DDB_0233205 antibody, zgc:109991 antibody, NADH:ubiquinone oxidoreductase core subunit S8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8a antibody, NADH:ubiquinone oxidoreductase core subunit S8 L homeolog antibody, NADH-quinone oxidoreductase subunit I antibody, NADH dehydrogenase Fe-S protein 8 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 8b antibody, NDUFS8 antibody, Ndufs8 antibody, ndufs8a antibody, ndufs8.L antibody, ndufs8 antibody, LOC551078 antibody, ndufs8b antibody
    背景
    NDUFS8 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (may donate electrons to ubiquinone). Defects in NDUFS8 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.Synonyms: CI-23kD, Complex I-23kD, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit, mitochondrial
    分子量
    24.0kDa (Mouse NP_659119.2 and Rat NP_001099792.1).
    基因ID
    4728
    NCBI登录号
    NP_002487
    UniProt
    O00217
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