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NCR1 抗体

NCR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499097
发货至: 中国
  • 抗原 See all NCR1 抗体
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    适用
    • 65
    • 48
    • 20
    • 9
    • 4
    • 4
    宿主
    • 55
    • 18
    • 9
    克隆类型
    • 58
    • 24
    多克隆
    标记
    • 33
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    This NCR1 antibody is un-conjugated
    应用范围
    • 47
    • 23
    • 21
    • 13
    • 13
    • 9
    • 7
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    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of CD335 / NKp46. (region surrounding Pro176)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product NCR1 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    别名
    CD335 / NKp46 (NCR1 产品)
    别名
    CD335 antibody, LY94 antibody, NK-p46 antibody, NKP46 antibody, Ly94 antibody, NKp46 antibody, KILR-1 antibody, Nk-p46 antibody, Nkp46 antibody, natural cytotoxicity triggering receptor 1 antibody, NCR1 antibody, Ncr1 antibody
    背景
    NKp46 (lymphocyte antigen 94, LY94) is a natural cytotoxicity receptor that belongs to the immunoglobulin superfamily and is expressed by all resting or activated NK cells, but not on T cells or B cells. The NKp46 cDNA encodes a 304 amino acid type I transmembrane protein with an extracellular region preceded by a 21 residue signal peptide and two cysteine-bridged C2-type Ig-like domains. A stem connects the extracellular domain to a 19 amino acid, arginine containing-transmembrane domain. NKp46 is involved in natural cytotoxicity and is involved in the recognition and lysis of both human and murine tumor cells.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
    分子量
    approx. 38 kDa
    基因ID
    9437
    NCBI登录号
    NP_004820
    UniProt
    O76036
    途径
    Regulation of Leukocyte Mediated Immunity
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