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FOLR1 抗体

FOLR1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499072
发货至: 中国
  • 抗原 See all FOLR1 抗体
    FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
    适用
    • 55
    • 18
    • 15
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 49
    • 15
    • 8
    • 1
    克隆类型
    • 58
    • 14
    • 1
    多克隆
    标记
    • 44
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOLR1 antibody is un-conjugated
    应用范围
    • 48
    • 40
    • 31
    • 21
    • 12
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of FR-α (Y80) protein. (region surrounding Tyr80)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product FOLR1 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
    别名
    Folate Receptor alpha (FOLR1 产品)
    别名
    FBP antibody, FOLR antibody, fbp antibody, folr antibody, folr1 antibody, FBP1 antibody, Folbp-1 antibody, Folbp1 antibody, Fbp1 antibody, FOLR1 antibody, Folr1 antibody, folate receptor 1 antibody, folate receptor 1 (adult) antibody, folate receptor 1 (adult) L homeolog antibody, zgc:165502 antibody, Folate receptor alpha antibody, folate receptor alpha antibody, FOLR1 antibody, folr1 antibody, folr1.L antibody, zgc:165502 antibody, Folr1 antibody, LOC100066084 antibody, LOC100725439 antibody
    背景
    Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
    分子量
    approx. 34 kDa
    基因ID
    2348
    NCBI登录号
    NP_000793
    UniProt
    P15328
    途径
    Dicarboxylic Acid Transport
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