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- 抗原 See all DPYSL4 抗体
- DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPYSL4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of CRMP-3 protein. (region surrounding Cys132)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product DPYSL4 Primary Antibody
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anti-Dihydropyrimidinase-Like 4 (DPYSL4) antibody
DPYSL4 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) (AA 461-559) antibodyDPYSL4 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) (AA 280-560) antibodyDPYSL4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) (AA 461-559) antibodyDPYSL4 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) (AA 1-572) antibodyDPYSL4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) (Internal Region) antibodyDPYSL4 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) antibodyDPYSL4 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidinase-Like 4 (DPYSL4) antibodyDPYSL4 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- DPYSL4 (Dihydropyrimidinase-Like 4 (DPYSL4))
- 别名
- DPYSL4 / CRMP3 (DPYSL4 产品)
- 别名
- CRMP3A antibody, CRMP3B antibody, crmp3 antibody, crmp3-a antibody, MGC53768 antibody, DPYSL4 antibody, drp-4 antibody, ulip4 antibody, CRMP-3 antibody, CRMP3 antibody, DRP-4 antibody, ULIP4 antibody, AI173505 antibody, Crmp3 antibody, DPY4 antibody, Drp-4 antibody, Ulip4 antibody, Dpys4 antibody, dihydropyrimidinase like 4 antibody, dihydropyrimidinase like 4 L homeolog antibody, dihydropyrimidinase-like 4 antibody, DPYSL4 antibody, dpysl4.L antibody, dpysl4 antibody, Dpysl4 antibody
- 背景
- Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to Semaphorin 3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia.Synonyms: Collapsin response mediator protein 3, DRP-4, Dihydropyrimidinase-related protein 4, ULIP4, UNC33-like phosphoprotein 4
- 分子量
- approx. 50 kDa
- 基因ID
- 10570
- NCBI登录号
- NP_006417
- UniProt
- O14531
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