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DHPS 抗体
DHPS
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
DHPS抗体详情
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抗原
See all DHPS 抗体
DHPS
(Deoxyhypusine Synthase (DHPS))
适用
All reactivities for DHPS 抗体
人
宿主
All hosts for DHPS 抗体
兔
克隆类型
All clonalities for DHPS 抗体
多克隆
标记
All conjugates for DHPS 抗体
This DHPS antibody is un-conjugated
应用范围
All applications for DHPS 抗体
Western Blotting (WB)
特异性
This antibody detects endogenous levels of DHS protein. (region surrounding Leu87)
交叉反应 (详细)
Species reactivity (tested):Human.
纯化方法
Affinity chromatography
纯度
> 95 % by SDS-PAGE
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Alternatives
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使用细节
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应用备注
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
DHPS目标详情
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抗原
DHPS
(Deoxyhypusine Synthase (DHPS))
Abstract
DHPS 产品
别名
MGC76269 antibody, zgc:56018 antibody, zgc:77325 antibody, wu:fb52g04 antibody, wu:fj48f12 antibody, zgc:111900 antibody, MGC82178 antibody, DDBDRAFT_0186679 antibody, DDBDRAFT_0266388 antibody, DDB_0186679 antibody, DDB_0266388 antibody, DHS antibody, DS antibody, MIG13 antibody, Dhs antibody, DYS antibody, EDA22 antibody, K18J17.7 antibody, K18J17_7 antibody, deoxyhypusine synthase antibody, embryo sac development arrest 22 antibody, deoxyhypusine synthase antibody, deoxyhypusine synthase S homeolog antibody, Deoxyhypusine synthase antibody, DHPS antibody, dhps antibody, dhps.S antibody, SHELL_RS05250 antibody, PF14_0125 antibody, CNJ02480 antibody, Tb10.70.4900 antibody, Tb927.1.870 antibody, MMAH_RS09430 antibody, TAGG_RS03310 antibody, TAGG_RS05175 antibody, Mesil_2448 antibody, Trad_0088 antibody, Igag_1842 antibody, Desac_0724 antibody, MZHIL_RS05480 antibody, MZHIL_RS05835 antibody, MZHIL_RS06250 antibody, Dhps antibody, DHS antibody
背景
Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.
分子量
approx. 45 kDa
基因ID
1725
NCBI登录号
NP_001921
UniProt
P49366
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