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CDC42EP2 抗体

CDC42EP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499043
发货至: 中国
  • 抗原 See all CDC42EP2 抗体
    CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))
    适用
    • 36
    • 15
    • 6
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 1
    克隆类型
    • 35
    • 1
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC42EP2 antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of Cdc42EP2 protein. (region surrounding Leu24)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CDC42EP2 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))
    别名
    CDC42EP2 (CDC42EP2 产品)
    别名
    CDC42EP2 antibody, zgc:103557 antibody, BORG1 antibody, CEP2 antibody, 1110008C05Rik antibody, Borg1 antibody, Cep2 antibody, D19Bwg1013e antibody, CDC42 effector protein 2 antibody, CDC42 effector protein 2 S homeolog antibody, CDC42 effector protein (Rho GTPase binding) 2 antibody, CDC42EP2 antibody, cdc42ep2.S antibody, cdc42ep2 antibody, Cdc42ep2 antibody
    背景
    Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.Synonyms: BORG1, Binder of Rho GTPases 1, CEP2, Cdc42 effector protein 2
    分子量
    approx. 30 kDa
    基因ID
    10435
    NCBI登录号
    NP_006770
    UniProt
    O14613
    途径
    Regulation of Actin Filament Polymerization
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