PAK3 抗体
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北京 101111
Quick Overview for PAK3 抗体 (ABIN499020)
抗原
See all PAK3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PAKbeta protein. (region surrounding asn148)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-PAK3 (PAK3) (AA 1-90) antibody
PAK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4G8F11 unconjugated
anti-PAK3 (PAK3) (AA 124-152) antibodyPAK3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 70-190) antibodyPAK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-PAK3 (PAK3) (AA 124-152), (N-Term) antibodyPAK3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34657 unconjugated
anti-PAK3 (PAK3) (Ser154) antibodyPAK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1223-1224 unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PAK3
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别名
- PAK3
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背景
- PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.Synonyms: Beta-PAK, OPHN3, Oligophrenin-3, PAK 3, PAK beta, PAK-3, Serine/threonine-protein kinase PAK 3, p21-activated kinase 3
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分子量
- approx. 70 kDa
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基因ID
- 5063
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NCBI登录号
- NP_001121645
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UniProt
- O75914
抗原
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