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PAK3 抗体 (AA 218-247)

PAK3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1223-1224 unconjugated
产品编号 ABIN392435
发货至: 中国
  • 抗原 See all PAK3 抗体
    PAK3
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 218-247
    适用
    • 70
    • 29
    • 18
    • 3
    宿主
    • 65
    • 5
    • 2
    克隆类型
    • 67
    • 6
    多克隆
    标记
    • 33
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK3 antibody is un-conjugated
    应用范围
    • 60
    • 40
    • 32
    • 13
    • 13
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PAK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the Central region of human PAK3.
    克隆位点
    RB1223-1224
    亚型
    Ig Fraction
    Top Product
    Discover our top product PAK3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PAK3
    别名
    PAK3 (PAK3 产品)
    别名
    CDKN1A antibody, MRX30 antibody, MRX47 antibody, OPHN3 antibody, PAK3beta antibody, bPAK antibody, hPAK3 antibody, PAK-3 antibody, Pak65alpha antibody, Pak65beta antibody, Stk4 antibody, beta-PAK antibody, XPak3 antibody, bpak antibody, cdkn1a antibody, mrx30 antibody, mrx47 antibody, ophn3 antibody, pak3 antibody, pak3-A antibody, pak3beta antibody, p21 (RAC1) activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog antibody, PAK3 antibody, Pak3 antibody, pak3.L antibody
    背景
    PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.
    分子量
    62310
    基因ID
    5063
    NCBI登录号
    NP_001121638, NP_001121639, NP_001121640, NP_001121644, NP_001121645, NP_002569
    UniProt
    O75914
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