PAK3 抗体 (pSer154)
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北京 101111
Quick Overview for PAK3 抗体 (pSer154) (ABIN6255002)
抗原
See all PAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer154
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特异性
- Phospho-PAK3 (Ser154) Antibody detects endogenous levels of PAK3 only when phosphorylated at Sersine 154.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human PAK3 around the phosphorylation site of Ser154.
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亚型
- IgG
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anti-PAK3 (PAK3) (AA 1-90) antibody
PAK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4G8F11 unconjugated
anti-PAK3 (PAK3) (AA 124-152) antibodyPAK3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 70-190) antibodyPAK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-PAK3 (PAK3) (AA 124-152), (N-Term) antibodyPAK3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34657 unconjugated
anti-PAK3 (PAK3) (Ser154) antibodyPAK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1223-1224 unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PAK3
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别名
- PAK3
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背景
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Description: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Gene: PAK3
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分子量
- 72kDa
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基因ID
- 5063
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UniProt
- O75914
抗原
-
