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- 抗原 See all PAK3 抗体
- PAK3
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抗原表位
- Ser154
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human PAK3 around the phosphorylation site of serine 154 (Y-M-S(p)-F-T).
- 亚型
- IgG
- Top Product
- Discover our top product PAK3 Primary Antibody
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anti-PAK3 (PAK3) (AA 1-90) antibody
PAK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人, 猴 WB, ELISA, IHC, Neut, FACS, ICC 宿主: 小鼠 Monoclonal 4G8F11 unconjugated
anti-PAK3 (PAK3) (AA 124-152) antibodyPAK3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 70-190) antibodyPAK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-PAK3 (PAK3) (AA 1-100) antibodyPAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) (AA 124-152), (N-Term) antibodyPAK3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34657 unconjugated
anti-PAK3 (PAK3) (AA 218-247) antibodyPAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK3 (PAK3) antibodyPAK3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PAK3
- 别名
- PAK3 (PAK3 产品)
- 别名
- CDKN1A antibody, MRX30 antibody, MRX47 antibody, OPHN3 antibody, PAK3beta antibody, bPAK antibody, hPAK3 antibody, PAK-3 antibody, Pak65alpha antibody, Pak65beta antibody, Stk4 antibody, beta-PAK antibody, XPak3 antibody, bpak antibody, cdkn1a antibody, mrx30 antibody, mrx47 antibody, ophn3 antibody, pak3 antibody, pak3-A antibody, pak3beta antibody, p21 (RAC1) activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog antibody, PAK3 antibody, Pak3 antibody, pak3.L antibody
- 背景
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Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Allen K.M., Nat. Genet. 20:25-30(1998).
Jiang C., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Kitano T., Mol. Biol. Evol. 20:1281-1289(2003).Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody
- UniProt
- O75914
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