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FOXO4 抗体
FOXO4
适用: 人, 小鼠, 大鼠
IHC (p)
宿主: 兔
Polyclonal
unconjugated
FOXO4抗体详情
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抗原
See all FOXO4 抗体
FOXO4
(Forkhead Box O4 (FOXO4))
适用
All reactivities for FOXO4 抗体
人, 小鼠, 大鼠
宿主
All hosts for FOXO4 抗体
兔
克隆类型
All clonalities for FOXO4 抗体
多克隆
标记
All conjugates for FOXO4 抗体
This FOXO4 antibody is un-conjugated
应用范围
All applications for FOXO4 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This antibody detects endogenous levels of FOXO4 protein. (region surrounding Ser203)
交叉反应 (详细)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
纯化方法
Affinity chromatography
纯度
> 95 % by SDS-PAGE
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使用细节
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应用备注
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
FOXO4目标详情
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抗原
FOXO4
(Forkhead Box O4 (FOXO4))
别名
FOXO4 / AFX1 / MLLT7 (FOXO4 产品 )
别名
FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
背景
FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulinresponse elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
分子量
approx. 55, 70 kDa
基因ID
4303
NCBI登录号
NP_005929
UniProt
P98177
途径
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Muscle Cell Differentiation
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