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EIF2S1 抗体 (pSer51)

Name: EIF2S1 抗体 (pSer51)
SKU: ABIN498760
Availability: OutOfStock

EIF2S1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot (WB) analyzes of p-eIF2alpha antibody in extracts from Jurkat insulin cells. (EIF2S1 抗体 (pSer51))

Immunohistochemistry (IHC) analyzes of p-eIF2alpha in paraffin-embedded human breast carcinoma tissue. (EIF2S1 抗体 (pSer51))

IHC (p)

2 images

产品编号 ABIN498760

发货至: 中国

Datasheet as PDF

抗原 See all EIF2S1 抗体

EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
抗原表位
18

9

8

6

5

5

4

3

2

1

1

1

1

1

1

1

1

1

1
pSer51
适用
66

40

30

9

8

7

7

6

6

6

5

5

4

3

2

1

1

1

1
人, 大鼠, 小鼠
宿主
72

9

2
兔
Compatible Secondaries
克隆类型
70

13
多克隆
标记
49

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This EIF2S1 antibody is un-conjugated
应用范围
55

37

31

28

15

13

13

10

6

6

3

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

This antibody detects endogenous levels of eIF2alpha protein only when phosphorylated at Ser51.

交叉反应（详细）

Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

纯化方法

Affinity chromatography

纯度

> 95 % by SDS-PAGE

Top Product

Discover our top product EIF2S1 Primary Antibody
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) antibody
EIF2S1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A5 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (N-Term) antibody
EIF2S1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1C6 unconjugated Recombinant Antibody

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer49) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibody
EIF2S1 适用: 人, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3H7 unconjugated

anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 276-315) antibody
EIF2S1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1,0 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

别名

EIF2A / EIF2S1 (EIF2S1 产品)

别名

EIF-2 antibody, EIF-2A antibody, EIF-2alpha antibody, EIF2 antibody, EIF2A antibody, Eif2s1 antibody, eif2s1l antibody, fb36a08 antibody, wu:fb36a08 antibody, zgc:56510 antibody, 0910001O23Rik antibody, 2410026C18Rik antibody, 35kDa antibody, Eif2a antibody, eIF2alpha antibody, eif2a antibody, CG9946 antibody, Dmel\\CG9946 antibody, Eif2alpha antibody, IF2A_DROME antibody, M(1)14C antibody, M(1)19-153 antibody, M(1)8e3-10 antibody, deIF2alpha antibody, eIF-2 antibody, eIF-2 a antibody, eIF-2 alpha antibody, eIF2 alpha antibody, eIF2-alpha antibody, eIF2a antibody, eiF-2alpha antibody, elF2alpha antibody, l(1)14Cf antibody, l(1)19-153 antibody, eukaryotic translation initiation factor 2 subunit alpha antibody, eukaryotic translation initiation factor 2, subunit 1 alpha a antibody, eukaryotic translation initiation factor 2, subunit 1 alpha antibody, eukaryotic translation initiation factor 2 alpha subunit antibody, Eukaryotic translation initiation factor 2 subunit 1 antibody, eukaryotic translation initiation factor 2 subunit alpha L homeolog antibody, eukaryotic translation Initiation Factor 2alpha antibody, EIF2S1 antibody, eif2s1a antibody, Eif2s1 antibody, eif2s1 antibody, LOC693063 antibody, CNI00230 antibody, THAPSDRAFT_105 antibody, if2a antibody, eif2s1.L antibody, eIF-2alpha antibody

背景

Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) is known to be an important translational control mechanism. Regulation of mammalian eIF2alpha activity is directly governed by specific phosphorylation on Serine 52. In mammalian cells, eIF2alpha is phosphorylated at Serine 52 by at least two kinases, the haem-controlled repressor and the interferon-inducible double stranded RNA-dependent protein kinase. This phosphorylation event results in an inhibition in the exchange of bound nucleotides and the recycling of eIF2alpha. In addition, phosphorylation of eIF2alpha blocks the GDP-GTP exchange activity of eIF2beta, resulting in the suppression of protein synthesis.Synonyms: EIF2-A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2 alpha

分子量

approx. 38 kDa

基因ID

1965

NCBI登录号

NP_004085

UniProt

P05198

途径

Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C