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DOK1 抗体 (pTyr362)

DOK1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498758
发货至: 中国
  • 抗原 See all DOK1 抗体
    DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
    抗原表位
    • 33
    • 28
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr362
    适用
    • 87
    • 49
    • 36
    • 7
    • 6
    • 6
    • 4
    • 2
    人, 小鼠, 大鼠
    宿主
    • 101
    • 2
    克隆类型
    • 101
    • 2
    多克隆
    标记
    • 46
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOK1 antibody is un-conjugated
    应用范围
    • 84
    • 31
    • 29
    • 18
    • 13
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of DOK1 protein only when phosphorylated at Tyr362.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product DOK1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
    别名
    DOK1 / p62 Dok (DOK1 产品)
    别名
    P62DOK antibody, Dok-1 antibody, AW557123 antibody, p62DOK antibody, dok1 antibody, zgc:76914 antibody, docking protein 1 antibody, docking protein 1b antibody, DOK1 antibody, Dok1 antibody, dok1b antibody
    背景
    Dok-1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Evidence suggests that p62 Dok-1 is a substrate of the constitutive tyrosine kinase activity of p210 Bcr-Abl, a fusion protein caused by the t(9,22) translocation and associated with chronic myelogenous leukemia. Dok-1, as well as the tyrosine kinase substrates IRS-1 and Cas, is a member of a class of Synonyms: Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62
    分子量
    approx. 62 kDa
    基因ID
    1796
    NCBI登录号
    NP_001372
    UniProt
    Q99704
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