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PRSS3 抗体

PRSS3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498692
发货至: 中国
  • 抗原 See all PRSS3 抗体
    PRSS3 (Protease, serine, 3 (PRSS3))
    适用
    • 43
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 2
    • 1
    • 1
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 19
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRSS3 antibody is un-conjugated
    应用范围
    • 35
    • 28
    • 23
    • 21
    • 9
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of Trypsin- 3 protein. (region surrounding Met166)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product PRSS3 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PRSS3 (Protease, serine, 3 (PRSS3))
    别名
    Trypsin-3 / PRSS3 (PRSS3 产品)
    别名
    MTG antibody, PRSS4 antibody, T9 antibody, TRY3 antibody, TRY4 antibody, Try3 antibody, Tb antibody, prss3 antibody, protease, serine 3 antibody, trypsin-3 antibody, protease, serine, 3 antibody, trypsin III antibody, protease, serine 3 L homeolog antibody, PRSS3 antibody, CpipJ_CPIJ016105 antibody, Prss3 antibody, trp-iii antibody, prss3.L antibody
    背景
    The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease Trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3 is expressed in the brain in addition to the pancreas.Synonyms: Brain trypsinogen, Mesotrypsinogen, PRSS4, Serine protease 3, Serine protease 4, TRY3, TRY4, Trypsin III, Trypsin IV
    分子量
    approx. 32 kDa
    基因ID
    5646
    NCBI登录号
    NP_002762
    UniProt
    P35030
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