TRAF6 抗体
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北京 101111
Quick Overview for TRAF6 抗体 (ABIN498675)
抗原
See all TRAF6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Mfn2 protein. (region surrounding His154)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 153-423) antibody
TRAF6 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 413-522) antibodyTRAF6 适用: 人 WB, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (Middle Region) antibodyTRAF6 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 441-530) antibodyTRAF6 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 314-343) antibodyTRAF6 适用: 人 WB 宿主: 兔 Polyclonal RB40708 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (C-Term) antibodyTRAF6 适用: 人, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) antibodyTRAF6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1950 unconjugated Recombinant Antibody
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
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别名
- TRAF6 / RNF85
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背景
- Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates adaptive immunity, innate immunity and bone metabolism. TRAF6 is a ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor beta-activated kinase (TAK1) and IkappaB kinase (IKK), by catalyzing the formation of a unique polyubiquitin chain linked through Lys 63 of Ub. TRAF6 is essential for activating NFκB signaling pathway in response to interleukin-1 and Toll-like receptor ligands. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination and activating NFkappaB signaling pathway. TRAF6 interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways.Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
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分子量
- approx. 58 kDa
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基因ID
- 7189
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NCBI登录号
- NP_004611
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UniProt
- Q9Y4K3
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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