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- 抗原 See all ACVR2A 抗体
- ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACVR2A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of ACTRIIA protein. (region surrounding His59)
- 交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product ACVR2A Primary Antibody
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- 应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).
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Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).
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- 抗原
- ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
- 别名
- Activin Receptor Type 2A (ACVR2A) (ACVR2A 产品)
- 别名
- ACVR2 antibody, ACVR2A antibody, XSTK9 antibody, actrii antibody, acvr2 antibody, ACTRII antibody, Acvr2 antibody, rActR-II antibody, actr2a antibody, acvr2a antibody, wu:fa02e10 antibody, ActrIIa antibody, TactrII antibody, activin A receptor type 2A antibody, activin A receptor type 2A L homeolog antibody, activin A receptor type 2Aa antibody, activin receptor IIA antibody, ACVR2A antibody, acvr2a antibody, Acvr2a antibody, acvr2a.L antibody, acvr2aa antibody
- 背景
- Members of the transforming growth factor beta superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTRIIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.Synonyms: ACTR-IIA, ACTRIIA, Activin A receptor type IIA
- 分子量
- approx. 48 kDa
- 基因ID
- 92
- NCBI登录号
- NP_001607
- UniProt
- P27037
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