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- 抗原 See all SCN2A 抗体
- SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SCN2A antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Na+ CP type II-alpha protein. (region surrounding Lys1032)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product SCN2A Primary Antibody
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anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) antibody
SCN2A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (Internal Region) antibodySCN2A 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (AA 467-485), (Intracellular) antibodySCN2A 适用: 人, 大鼠, 小鼠 IHC, WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (AA 273-362) antibodySCN2A 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (AA 275-401) antibodySCN2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (C-Term) antibodySCN2A 适用: 大鼠 IHC, WB, IP, FM 宿主: 小鼠 Monoclonal S69-3 unconjugated
anti-Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A) (AA 467-485), (Intracellular) antibodySCN2A 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 豚鼠 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))
- 别名
- SCN2A (SCN2A 产品)
- 别名
- SCN2A2 antibody, 6430408L10 antibody, A230052E19Rik antibody, Nav1.2 antibody, Scn2a antibody, NachII antibody, RII/RIIA antibody, RNSCPIIR antibody, SCN antibody, SCN2A antibody, Scn2a2 antibody, ScpII antibody, BFIC3 antibody, BFIS3 antibody, BFNIS antibody, EIEE11 antibody, HBA antibody, HBSCI antibody, HBSCII antibody, NAC2 antibody, Na(v)1.2 antibody, SCN2A1 antibody, sodium voltage-gated channel alpha subunit 2 antibody, sodium channel protein type 2 subunit alpha antibody, sodium channel, voltage-gated, type II, alpha antibody, sodium channel, voltage-gated, type II, alpha subunit antibody, SCN2A antibody, LOC100217927 antibody, LOC100389294 antibody, LOC100484218 antibody, Scn2a antibody, LOC478773 antibody
- 背景
- Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The three glycoproteins that comprise the voltagegated sodium channel proteins include a pore-forming alpha subunit, a noncovalently associated beta1 subunit and a disulfidelinked beta2 subunit. The two beta subunits regulate the level of channel expression, modulate gating and function as cell adhesion molecules for cellular aggregation and cytoskeleton interaction. The alpha subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type IIalpha subunits are more abundant along axons. The beta1 subunit of sodium channel type I is expressed in brain, skeletal and cardiac muscle. In the brain, beta1 and beta2 are highly expressed in Purkinje cells, and beta1 is also expressed in the pyramidal cells of the deep cerebellar nuclei. Impaired voltage-gated sodium channels lead to a number of diseases including myotonia.Synonyms: HBSC II, NAC2, SCN2A1, SCN2A2, Sodium channel protein brain II subunit alpha, Sodium channel protein type 2 subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.2
- 基因ID
- 6326
- NCBI登录号
- NP_001035232
- UniProt
- Q99250
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