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MEIS1 抗体

MEIS1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498509
发货至: 中国
  • 抗原 See all MEIS1 抗体
    MEIS1 (Meis Homeobox 1 (MEIS1))
    适用
    • 44
    • 28
    • 17
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    人, 小鼠
    宿主
    • 41
    • 2
    • 1
    克隆类型
    • 35
    • 9
    多克隆
    标记
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MEIS1 antibody is un-conjugated
    应用范围
    • 23
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of Meis1 protein. (region surrounding Ile278)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product MEIS1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MEIS1 (Meis Homeobox 1 (MEIS1))
    别名
    MEIS1 (MEIS1 产品)
    别名
    meis antibody, 1323/07 antibody, 1422/04 antibody, CG17117 antibody, Dm-HTH antibody, Dmel\\CG17117 antibody, HTH antibody, Hth antibody, Meis1 antibody, P53 antibody, anon-EST:Liang-2.13 antibody, clone 2.13 antibody, dtl antibody, hth1 antibody, hth2 antibody, l(3)05745 antibody, l(3)86Ca antibody, cb224 antibody, id:ibd5078 antibody, meis1.1 antibody, wu:fb38b03 antibody, wu:fc02e11 antibody, wu:fd12a02 antibody, C530044H18Rik antibody, Evi8 antibody, Meis homeobox 1 antibody, Meis homeobox 1 S homeolog antibody, homothorax antibody, Meis homeobox 1 b antibody, MEIS1 antibody, meis1.S antibody, Meis1 antibody, hth antibody, meis1b antibody, meis1 antibody
    背景
    Hox, Pbx, and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Hox proteins are involved in regulating tissue patterning during development, and they are also expressed n lineage- and stage-specific patterns during adult ematopoietic ifferentiation and in leukemias. The Hox proteins, which include paralog groups 1 to 10, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx related Meis proteins, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site. Both Meis1 and 2 (also known as Meis-related gene 1) are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. In addition to binding with Hox proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA-binding specificities.Synonyms: Homeobox protein Meis1
    分子量
    approx. 37 kDa
    基因ID
    4211
    NCBI登录号
    NP_002389
    UniProt
    O00470
    途径
    Chromatin Binding
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