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- 抗原 See all BNIP2 抗体
- BNIP2 (BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BNIP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of BNIP-2 protein. (region surrounding Glu122)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product BNIP2 Primary Antibody
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 1-314) antibody
BNIP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8C6 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (Internal Region) antibodyBNIP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 125-280) antibodyBNIP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) antibodyBNIP2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (Internal Region) antibodyBNIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 6-229) antibodyBNIP2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 285-316) antibodyBNIP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (C-Term) antibodyBNIP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (C-Term) antibodyBNIP2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 152-201) antibodyBNIP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- BNIP2 (BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2))
- 别名
- BNIP2 (BNIP2 产品)
- 别名
- BNIP-2 antibody, NIP2 antibody, 5730523P12Rik antibody, BNIP2beta antibody, Nip21 antibody, BCL2 interacting protein 2 antibody, BCL2/adenovirus E1B interacting protein 2 antibody, BNIP2 antibody, Bnip2 antibody
- 背景
- The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, NIP2
- 分子量
- approx. 34 kDa
- 基因ID
- 663
- NCBI登录号
- NP_004321
- UniProt
- Q12982
- 途径
- Regulation of Muscle Cell Differentiation
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