PIK3CA 抗体
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北京 101111
Quick Overview for PIK3CA 抗体 (ABIN498480)
抗原
See all PIK3CA 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PI 3-kinase p110alpha protein. (region surrounding Arg519)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 401-600) antibody
PIK3CA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) antibodyPIK3CA 适用: 人 WB, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 961-1068) antibodyPIK3CA 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 1019-1050), (C-Term) antibodyPIK3CA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01702 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 504-533) antibodyPIK3CA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (pTyr317) antibodyPIK3CA 适用: 人, 小鼠, Cow WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Internal Region) antibodyVerified PIK3CA 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (N-Term) antibodyPIK3CA 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 959-1068) antibodyPIK3CA 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Catalytic Subunit) antibodyPIK3CA 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 10E5 unconjugated Recombinant Antibody
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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别名
- PIK3CA
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背景
- Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of 85 kDa (p85) and 110 kDa (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85alpha and p85beta), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110alpha and p110beta interact with p85alpha, and p110alpha has also been shown to interact with p85beta in vitro. p110delta expression is restricted to white blood cells. It has been shown to bind p85alpha and beta, but it apparently does not phosphorylate these subunits. p110delta seems to have the capacity to autophosphorylate. p110gamma does not interact with the p85 subunits. It has been shown to be activated by alpha and beta-gamma heterotrimeric G proteins.Synonyms: 5-bisphosphate 3-kinase catalytic subunit alpha isoform, EC=2.7.1.153, PI3-kinase p110 subunit alpha, PI3K, PIK3CA, Phosphatidylinositol-4, PtdIns-3-kinase p110
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分子量
- approx. 110 kDa
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基因ID
- 5290
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NCBI登录号
- NP_006209
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UniProt
- P42336
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途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
抗原
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