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INHBC 抗体

INHBC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498474
发货至: 中国
  • 抗原 See all INHBC 抗体
    INHBC (Inhibin, beta C (INHBC))
    适用
    • 28
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    宿主
    • 47
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    克隆类型
    • 48
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    多克隆
    标记
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    This INHBC antibody is un-conjugated
    应用范围
    • 27
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Inhibin beta-C protein. (region surrounding Val129)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product INHBC Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    INHBC (Inhibin, beta C (INHBC))
    别名
    Inhibin beta C Chain (INHBC) (INHBC 产品)
    别名
    IHBC antibody, inhibin beta C subunit antibody, inhibin beta-C antibody, INHBC antibody, Inhbc antibody
    背景
    The TGFbeta superfamily is composed of numerous growth and differentiation factors, including transforming growth factor beta (TGFbeta) 1, 2 and 3, growth/differentiation factor (GDF) 1 through 8, Mullerian inhibiting substance (MIS), bone morphogenic protein (BMP) 2 through 8, glial cell linederived neurotrophic factor (GDNF), inhibins (alpha, beta-A, beta-B and beta-C), Lefty and Nodal. Members of the TGFbeta superfamily are involved in embryonic development and adult tissue homeostasis. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth depending on their subunit composition. Activins oppose the funtions of inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue, but also in benign prostatic hyperplasia. Inhibin A, a dimer of alpha and beta-A, and inhibin B, a dimer of alpha and beta-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin beta-C forms a homodimer and its expression is predominant in adult liver and in benign prostatic hyperplasia.Synonyms: Activin C, Activin beta-C chain
    分子量
    approx. 30 kDa
    基因ID
    3626
    NCBI登录号
    NP_005529
    UniProt
    P55103
    途径
    Peptide Hormone Metabolism, Hormone Activity
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