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- 抗原 See all TCEB3 抗体
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCEB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Elongin A1 protein. (region surrounding Arg129)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product TCEB3 Primary Antibody
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anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 76-345) antibody
TCEB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 1-772) antibodyTCEB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 81-190) antibodyTCEB3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 200-344) antibodyTCEB3 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 679-798) antibodyTCEB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) antibodyTCEB3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 1-772) antibodyTCEB3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (N-Term) antibodyTCEB3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (C-Term) antibodyTCEB3 适用: 人, 猴, 犬, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) (AA 679-798) antibodyTCEB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- 别名
- TCEB3 (TCEB3 产品)
- 别名
- CG6755 antibody, Dmel\\CG6755 antibody, Elo-A antibody, dEloA antibody, tceb3a antibody, zgc:56638 antibody, wu:fw66g10 antibody, TCEB3 antibody, 110kDa antibody, AA408125 antibody, Tceb3a antibody, El antibody, EloA antibody, SIII antibody, SIII p110 antibody, TCEB3A antibody, Elongin A antibody, transcription elongation factor B polypeptide 3 antibody, elongin A antibody, calcium binding and coiled-coil domain 1b antibody, elongin A S homeolog antibody, transcription elongation factor B subunit 3 antibody, EloA antibody, LOC413407 antibody, eloa antibody, calcoco1b antibody, ELOA antibody, eloa.S antibody, Eloa antibody, TCEB3 antibody
- 背景
- Individuals harboring germline mutations in the tumor suppressor gene von Hippel-Lindau (VHL) exhibit an increased susceptibility to a variety of tumors including renal carcinom,a hemangio-blastoma of the central nervous system and pheochromo-cytoma. The Elongin (SIII) complex has been identified as the functional target of the VHL protein. Elongin (SIII) is a heterotrimer composed of a transcriptional active subunit designated Elongin A and two regulatory subunits designated Elongin B and Elongin C. VHL functions by binding to the Elongin B and C subunits, inhibiting the transcriptional efficacy of the Elongin (SIII) complex. The VHL protein migrates with an apparent molecular weight of 38 kDa. The Elongin A subunit is 773 amino acids in length and has an apparent molecular weight of 110 kD,a while Elongin B and C are 18 kDa and 15 kDa proteins, respectively.Synonyms: EloA, Elongin 110 kDa subunit, Elongin A, Elongin-A, RNA polymerase II transcription factor SIII subunit A1, Transcription elongation factor B polypeptide 3
- 分子量
- approx. 78 kDa
- 基因ID
- 6924
- NCBI登录号
- NP_003189
- UniProt
- Q14241
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