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DUSP9 抗体

DUSP9 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498354
发货至: 中国
  • 抗原 See all DUSP9 抗体
    DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))
    适用
    • 42
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 39
    • 3
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP9 antibody is un-conjugated
    应用范围
    • 31
    • 23
    • 19
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of MKP-4 protein. (region surrounding Ala174)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product DUSP9 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))
    别名
    DUSP9 / MKP4 (DUSP9 产品)
    别名
    MKP-4 antibody, MKP4 antibody, Dusp4 antibody, Mpk4 antibody, Pyst3 antibody, DUSP9 antibody, dual specificity phosphatase 9 antibody, DUSP9 antibody, Dusp9 antibody
    背景
    Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4. Human MKP-1 maps to chromosome 5q34 and encodes a 367 amino acid, 39 kDa protein that dephosphorylates MAP kinase ERK2 on both Thr-183 and Tyr-185.Synonyms: Dual specificity protein phosphatase 9, MAP kinase phosphatase 4, Mitogen-activated protein kinase phosphatase 4
    分子量
    approx. 42 kDa
    基因ID
    1852
    NCBI登录号
    NP_001386
    UniProt
    Q99956
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