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FOXE3 抗体

FOXE3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498337
发货至: 中国
  • 抗原 See all FOXE3 抗体
    FOXE3 (Forkhead Box E3 (FOXE3))
    适用
    • 35
    • 13
    • 13
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOXE3 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of FOXE3 protein. (region surrounding Arg97)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product FOXE3 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % Sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOXE3 (Forkhead Box E3 (FOXE3))
    别名
    FOXE3 / FKHL12 (FOXE3 产品)
    别名
    FOXE3 antibody, FKHL12 antibody, FREAC8 antibody, dyl antibody, rct antibody, FREAC-8 antibody, HFH7 antibody, HNF3 antibody, foxe4 antibody, lens1 antibody, lens1-A antibody, forkhead box E3 antibody, forkhead box E3 L homeolog antibody, foxe3 antibody, FOXE3 antibody, LOC100301611 antibody, Foxe3 antibody, foxe3.L antibody
    背景
    The human forkhead-box (FOX) gene family consists of at least 43 members, including FOXE3, a 288-amino acid protein. FOXE3 is a winged-helix transcription factor that plays a crucial role during the initial stages of lens development and closure of the lens vesicle. FOXE3 may also act as a factor that promotes survival and proliferation while preventing differentiation in the lens epithelium. As the posterior cells of the lens fiber begin to differentiate, expression of FOXE3 is limited to the undifferentiated cells coating the anterior surface of the lens. Congenital primary aphakia (CPA) is a rare developmental disorder caused by a null mutation in the FOXE3 gene that is identified by the absence of a lens. The development of CPA is normally stimulated during the fourth or fifth week of human embryogenesis.Synonyms: FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8
    分子量
    approx. 33 kDa
    基因ID
    2301
    NCBI登录号
    NP_036318
    UniProt
    Q13461
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