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- 抗原 See all DUSP4 抗体
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DUSP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MKP-2 protein. (region surrounding Tyr108)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product DUSP4 Primary Antibody
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anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 1-394) antibody
DUSP4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (Internal Region) antibodyDUSP4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 1-394) antibodyDUSP4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 1-394) antibodyDUSP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D6-G6 unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (C-Term) antibodyDUSP4 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 109-198) antibodyDUSP4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) antibodyDUSP4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 1-168) antibodyDUSP4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (AA 331-361), (C-Term) antibodyDUSP4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB05733 unconjugated
anti-Dual Specificity Phosphatase 4 (DUSP4) (Internal Region) antibodyDUSP4 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- 别名
- DUSP4 (DUSP4 产品)
- 别名
- zgc:55423 antibody, DUSP4 antibody, typ antibody, hvh2 antibody, mkp2 antibody, mkp-2 antibody, MGC131045 antibody, HVH2 antibody, MKP-2 antibody, MKP2 antibody, TYP antibody, 2700078F24Rik antibody, AI844617 antibody, BB104621 antibody, E130306H24Rik antibody, Mkp-2 antibody, Mkp2 antibody, dual specificity phosphatase 4 antibody, dual specificity phosphatase 4 S homeolog antibody, dusp4 antibody, DUSP4 antibody, dusp4.S antibody, Dusp4 antibody
- 背景
- Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP- 4. Human MKP-2 maps to chromosome 8p12-p11 and encodes a 394 amino acid, 43 kDa protein that specifically inactivates ERK1, ERK2 and JNK.Synonyms: Dual specificity protein phosphatase 4, Dual specificity protein phosphatase hVH2, MKP2, Mitogen-activated protein kinase phosphatase 2, VH2
- 基因ID
- 1846
- NCBI登录号
- NP_001385
- UniProt
- Q13115
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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