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FOXL1 抗体

FOXL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498334
发货至: 中国
  • 抗原 See all FOXL1 抗体
    FOXL1 (Forkhead Box L1 (FOXL1))
    适用
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    宿主
    • 40
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    克隆类型
    • 42
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    多克隆
    标记
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    This FOXL1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of FoxL1 protein. (region surrounding Gly150)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product FOXL1 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOXL1 (Forkhead Box L1 (FOXL1))
    别名
    FOXL1 / FKHL11 (FOXL1 产品)
    别名
    zgc:63595 antibody, FOXL1 antibody, fkh6 antibody, fkhl11 antibody, freac7 antibody, CG1132 antibody, Dmel\\CG1132 antibody, Dmfd2 antibody, FD2 antibody, FoxL1 antibody, fd2 antibody, Foxl1 antibody, FKH6 antibody, FKHL11 antibody, FREAC7 antibody, Fkh6 antibody, fkh-6 antibody, forkhead box L1 antibody, forkhead domain 64A antibody, forkhead transcription factor L1 antibody, forkhead box L1 transcription factor antibody, foxl1 antibody, FOXL1 antibody, fd64A antibody, LOC579718 antibody, Foxl1 antibody
    背景
    FOXL1 is a 337 amino acid protein encoded by the mouse gene Foxl1. FOXL1 belongs to the fork head family and contains one fork head DNA-binding domain. The HNF3/fork head family includes a large number of transcription factors that share a structurally related DNA binding domain. Fork head factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1- deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the adenomatous polyposis coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.Synonyms: FREAC7, Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7
    分子量
    approx. 36 kDa
    基因ID
    2300
    NCBI登录号
    NP_005241
    UniProt
    Q12952
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